HPLC CHROMATOGRAPHY HINTS and TIPS FOR CHROMATOGRAPHERS [HPLC TRAINING ARTICLES]

The HPLC "Hints and Tips" found here will be of interest to anyone performing HPLC, UHPLC (UPLC), LC/MS, SFC, CE or GC analysis. Many of these free tips, taken from professional classes that I teach, discuss fundamental to advanced level chromatography concepts in a practical way. Occasionally, I will also include laboratory computer related tips here too. Please "follow" this blog to receive updates of new posts. Hint: Type keywords into the SEARCH bar to quickly find other articles.

Saturday, February 10, 2018

HPLC Baseline Stabilization Tips for Refractive Index Detectors (RI or RID)

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If you use refractive index detection (RID) for your HPLC samples, then you are already familiar with the very long equilibration periods ne...
Saturday, January 6, 2018

UHPLC TIP: Reducing the Column Temperature to Offset Frictional Heating Effects (Causing Poor Resolution)

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HPLC column temperature is a critical variable that we adjust and optimize during method development. We use it as a variable during the m...
Saturday, December 9, 2017

Evaporative HPLC Detectors; CAD (Charged Aerosol Detector) and ELSD (Evaporative Light-Scattering Detector)

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If you wish to read about their development and/or operating principles, then please review the early published patents and many arti...
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Saturday, November 4, 2017

Repair Missing Or Corrupted Windows System Files Using the System File Checker Tool

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It has been awhile since I posted any Microsoft Windows software tools or tips so here is a MS utility program. Most laboratory instruments ...
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HPLC EXPERT
AKA: "The HPLC Doctor". An expert Chromatographer, Scientist, Consultant and Inventor who works in the Analytical, BioMedical, BioPharma, Medicinal Chemistry, Medical Device and Product Engineering fields. I enjoy teaching, working with and training scientists to use different types of analytical instrumentation to solve challenging problems.
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