HPLC CHROMATOGRAPHY HINTS and TIPS FOR CHROMATOGRAPHERS [HPLC TRAINING ARTICLES]

The HPLC "Hints and Tips" found here will be of interest to anyone performing HPLC, UHPLC (UPLC), LC/MS, SFC, CE or GC analysis. Many of these free tips, taken from professional classes that I teach, discuss fundamental to advanced level chromatography concepts in a practical way. Occasionally, I will also include laboratory computer related tips here too. Please "follow" this blog to receive updates of new posts. Hint: Type keywords into the SEARCH bar to quickly find other articles.

Showing posts with label Buffer. Show all posts
Showing posts with label Buffer. Show all posts
Saturday, October 31, 2020

Capillary Electrophoresis (CE) Troubleshooting Tips:

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What follows is a short list of problems, "observations" followed by a list of areas that should be investigated, as appropriate i...
Saturday, December 26, 2015

Common pKa Values for ACIDS & BASES used in HPLC and LC/MS Method Development

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pKa (25°C)                              ACID 0.3                                           Trifluoroacetic acid 2.15           ...
3 comments:
Saturday, May 30, 2015

HPLC Peak Tailing - Some of the Most Common Reasons For it

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Three easy ways to minimize chromatography peak tailing: (1) Tailing often results from using “Type – A” HPLC silica. Type-A sili...
Saturday, June 14, 2014

Popular LC/MS and HPLC Volatile Mobile Phase Modifiers

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For applications which utilize an Evaporative Light Scattering Detector (E.L.S.D.), Charged Aerosol Detector (CAD) and/or Mass Spectrometer ...
6 comments:
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HPLC EXPERT
AKA: "The HPLC Doctor". An expert Chromatographer, Scientist, Consultant and Inventor who works in the Analytical, BioMedical, BioPharma, Medicinal Chemistry, Medical Device and Product Engineering fields. I enjoy teaching, working with and training scientists to use different types of analytical instrumentation to solve challenging problems.
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